N6,2′-O-Dimethyladenosine

Names

[ Name ]:
N6,2′-O-Dimethyladenosine

[Synonym ]:
2'-O-methyl-N6-methyladenosine
6-N,2'-O-dimethyladenosine
N6,2'-O-Dimethyladenosine
N6,O2'-dimethyl-adenosine

Biological Activity

[Description]:

N6,2′-O-Dimethyladenosine, a substrate of fat mass and obesity-associated gene (FTO), is a reversible modification widely occurred on varied RNA molecules. N6,2′-O-Dimethyladenosine can regulate obesity[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Ben-Haim MS, et, al. Dynamic regulation of N 6,2'-O-dimethyladenosine (m 6 Am) in obesity. Nat Commun. 2021 Dec 10;12(1):7185.

[2]. Jiang J, et, al. m6AmPred: Identifying RNA N6, 2'-O-dimethyladenosine (m 6 A m) sites based on sequence-derived information. Methods. 2021 Feb 2;S1046-2023(21)00019-0.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₁₇N₅O₄

[ Molecular Weight ]:
295.29400

[ Exact Mass ]:
295.12800

[ PSA ]:
114.55000

Related Compounds

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