5-Methyl-2-nitroaniline

Names

[ CAS No. ]:
578-46-1

[ Name ]:
5-Methyl-2-nitroaniline

[Synonym ]:
5-Methyl-2-nitroaniline
Benzenamine, 5-methyl-2-nitro-
MFCD00007814
EINECS 209-423-7

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
312.4±22.0 °C at 760 mmHg

[ Melting Point ]:
110-111 °C(lit.)

[ Molecular Formula ]:
C₇H₈N₂O₂

[ Molecular Weight ]:
152.151

[ Flash Point ]:
142.8±22.3 °C

[ Exact Mass ]:
152.058578

[ PSA ]:
71.84000

[ LogP ]:
2.29

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.616

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XU8060000

CHEMICAL NAME :: m-Toluidine, 6-nitro-

CAS REGISTRY NUMBER :: 578-46-1

BEILSTEIN REFERENCE NO. :: 2691416

LAST UPDATED :: 199803

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H8-N2-O2

MOLECULAR WEIGHT :: 152.17

WISWESSER LINE NOTATION :: WNR BZ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 500 ug/plate

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,163,1982

Safety Information

[ Symbol ]:

GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311 + H331-H373-H411

[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P311

[ Hazard Codes ]:
T: Toxic;N: Dangerous for the environment;

[ Risk Phrases ]:
R23/24/25;R33;R51/53

[ Safety Phrases ]:
S28-S36/37-S45-S61

[ RIDADR ]:
UN 2660 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
XU8060000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2921430090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921430090

[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis and histone deacetylase inhibitory activity of new benzamide derivatives.

J. Med. Chem. 42(15) , 3001-3, (1999)

Newly synthesized benzamide derivatives were evaluated for their inhibitory activity against histone deacetylase. The structure of these derivatives was unrelated to the known inhibitors, and IC(50) v...