Ledol

Names

[ CAS No. ]:
577-27-5

[ Name ]:
Ledol

[Synonym ]:
(1aR-(1aα,4α,4aβ,7α,7aβ,7bα))-decahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulen-4-ol
(1aR,4R,4aS,7R,7aS,7bS)-1,1,4,7-Tetramethyl-decahydro-cyclopropa[e]azulen-4-ol

Biological Activity

[Description]:

Ledol ((+)-Ledol) is an antifungal agent that can be isolated from the essential oil fractions of Rhododendron tomentosum. Ledol is also the expectorant and antitussive agent, which is simultaneously responsible for adverse reactions such as dizziness, nausea and vomiting[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Jesionek A, et al. Validated HPTLC method for determination of ledol and alloaromadendrene in the essential oil fractions of Rhododendron tomentosum plants and in vitro cultures and bioautography for their activity screening. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jun 1;1086:63-72.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₂₆O

[ Molecular Weight ]:
222.36600

[ Exact Mass ]:
222.19800

[ PSA ]:
20.23000

[ LogP ]:
3.46570