Methyl 2-sulfamoylbenzoate
Names
[ CAS No. ]:
57683-71-3
[ Name ]:
Methyl 2-sulfamoylbenzoate
[Synonym ]:
2-Aminosulfonyl-benzoic acid methyl ester
Methyl 2-sulfamoylbenzoate
o-Carbomethoxybenzene sufonamide
MFCD00009808
Benzoic acid, 2-(aminosulfonyl)-, methyl ester
2-Carbomethoxybenzenesulfonamide
EINECS 260-903-2
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
401.4±47.0 °C at 760 mmHg
[ Melting Point ]:
126-128 °C(lit.)
[ Molecular Formula ]:
C8H9NO4S
[ Molecular Weight ]:
215.226
[ Flash Point ]:
196.6±29.3 °C
[ Exact Mass ]:
215.025223
[ PSA ]:
94.84000
[ LogP ]:
0.30
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.557
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DH6830000
- CHEMICAL NAME :
- Benzoic acid, 2-sulfamoyl-, methyl ester
- CAS REGISTRY NUMBER :
- 57683-71-3
- BEILSTEIN REFERENCE NO. :
- 2728611
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C8-H9-N-O4-S
- MOLECULAR WEIGHT :
- 215.24
- WISWESSER LINE NOTATION :
- ZSWR BVO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia Musculoskeletal - other changes
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 13,144,1979
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
DH6830000
[ HS Code ]:
2935009090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2935009090
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%
Articles
Rapid Commun. Mass Spectrom. 29 , 1370-80, (2015)
Sulfonylureas are among the most important class of antidiabetic and herbicides. Solar light excitation and Advanced Oxidation Processes may result in the formation of a wide array of products owing t...
Preparation of 2-(1-Phenyl-1H-pyrazol-5-yl) benzenesulfonamides from Polylithiated C (alpha), N-Phenylhydrazones and Methyl 2-(Aminosulfonyl) benzoate.J. Heterocycl. Chem. 42(6) , 1095, (2005)