6,7-dimethyl-5-phenyl-1,3-dihydropyrrolo[3,4-e][1,4]diazepin-2-one
Names
[ CAS No. ]:
57435-86-6
[ Name ]:
6,7-dimethyl-5-phenyl-1,3-dihydropyrrolo[3,4-e][1,4]diazepin-2-one
[Synonym ]:
Premazepam
MDL 181
3,7-dihydro-6,7-dimethyl-5-phenyl-pyrrolo[3,4-e][1,4]-diazepine-2-(1H)-one
Premazepamum [INN-Latin]
6,7-dimethyl-5-phenyl-3,7-dihydro-1H-pyrrolo[3,4-e][1,4]diazepin-2-one
3,7-Dihydro-6,7-dimethyl-5-phenylpyrrolo(3,4-e)-1,4-diazepin-2(1H)-one
Chemical & Physical Properties
[ Molecular Formula ]:
C15H15N3O
[ Molecular Weight ]:
253.29900
[ Exact Mass ]:
253.12200
[ PSA ]:
46.39000
[ LogP ]:
1.69660
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UY8558000
- CHEMICAL NAME :
- Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-6,7-dimethyl-5-phenyl-
- CAS REGISTRY NUMBER :
- 57435-86-6
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C15-H15-N3-O
- MOLECULAR WEIGHT :
- 253.33
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 11,217,1976