2-Bromo-5-fluorobenzonitrile

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
251.2±25.0 °C at 760 mmHg

[ Melting Point ]:
92-95 °C(lit.)

[ Molecular Formula ]:
C₇H₃BrFN

[ Molecular Weight ]:
200.008

[ Flash Point ]:
105.7±23.2 °C

[ Exact Mass ]:
198.943283

[ PSA ]:
23.79000

[ LogP ]:
1.97

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.578

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
3439

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2926909090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Facile synthesis of 2-bromo-3-fluorobenzonitrile: An application and study of the halodeboronation of aryl boronic acids. Szumigala RH, et al.

J. Org. Chem. 69(2) , 566-569, (2004)

The Expedient Synthesis of 4, 2'-Difluoro-5'-(7-trifluoromethyl-imidazo [1,2-a] pyrimidin-3-yl) biphenyl-2-carbonitrile, a GABA α2/3 Agonist. Cameron M, et al.

Org. Process Res. Dev. 10(3) , 398-402, (2006)

Large-scale applications of transition metal-catalyzed couplings for the synthesis of pharmaceuticals. Magano J and Dunetz JR.

Chem. Rev. 111(3) , 2177-2250, (2011)

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