Rhamnocitrin

Names

[ CAS No. ]:
569-92-6

[ Name ]:
Rhamnocitrin

[Synonym ]:
3,5,4'-trihydroxy-7-methoxyflavone
Rhamnocitrin
3,4',5-Trihydroxy-7-methoxyflavone
3,5-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one
5,4'-dihydroxy-7-methoxyflavonol
kaempferol 7-O-methyl ether
4H-1-Benzopyran-4-one, 3,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-
7-Methylkaempferol
3,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one

Biological Activity

[Description]:

Rhamnocitrin is a flavonoid isolated from astragalus complanatus R. Br. (Sha-yuan-zi)[1]. Rhamnocitrin is a scavenger of DPPH with an IC50 of 28.38 mM. Rhamnocitrin has anti-oxidant, anti-inflammatory and an-tiatherosclerosis activity[2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Li Y, et al. Simultaneous Determination of Formononetin, Calycosin and Rhamnocitrin from Astragalus Complanatus by UHPLC-MS-MS in Rat Plasma: Application to a Pharmacokinetic Study. J Chromatogr Sci. 2016 Jun 19.

[2]. Tu YC, et al. Antiatherogenic effects of kaempferol and rhamnocitrin. J Agric Food Chem. 2007 Nov 28;55(24):9969-76.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
571.9±50.0 °C at 760 mmHg

[ Melting Point ]:
225-227ºC

[ Molecular Formula ]:
C₁₆H₁₂O₆

[ Molecular Weight ]:
300.263

[ Flash Point ]:
218.4±23.6 °C

[ Exact Mass ]:
300.063385

[ PSA ]:
100.13000

[ LogP ]:
2.56

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.710

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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