E 537
Names
[ CAS No. ]:
5657-61-4
[ Name ]:
E 537
[Synonym ]:
Nicoxamat
3-picolinehydroxamic acid
E 537
3-pyridinehydroxamic acid
nicotinic acid hydroxamate
N-Hydroxy-3-pyridinecarboxamide
Nicotinohydroximic acid
Nicotinohydroxamsaeure
N-Hydroxynicotinamid
Nicotine hydroxamic acid
nicotinohydroxamic acid
3-Pyridinecarboxamide,N-hydroxy
3-pyridinecarbohydroxamic acid
Nicotinylhydroxamic acid
Chemical & Physical Properties
[ Density]:
1.328g/cm3
[ Molecular Formula ]:
C6H6N2O2
[ Molecular Weight ]:
138.12400
[ Exact Mass ]:
138.04300
[ PSA ]:
62.22000
[ LogP ]:
0.59150
[ Index of Refraction ]:
1.585
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US4666100
- CHEMICAL NAME :
- 3-Pyridinecarboxamide, N-hydroxy-
- CAS REGISTRY NUMBER :
- 5657-61-4
- BEILSTEIN REFERENCE NO. :
- 0003657
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C6-H6-N2-O2
- MOLECULAR WEIGHT :
- 138.14
- WISWESSER LINE NOTATION :
- T6NJ CVMQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 1 mmol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 29,1275,1980
Safety Information
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
26-36