Bis(2-chloroethyl)aminomethyl-4-hydroxynitrobenzene
Names
[ CAS No. ]:
56537-91-8
[ Name ]:
Bis(2-chloroethyl)aminomethyl-4-hydroxynitrobenzene
[Synonym ]:
2-((Bis(2-chloroethyl)amino)methyl)-4-nitrophenol
Phenol,2-((bis(2-chloroethyl)amino)methyl)-4-nitro
2-[N.N-Bis-(2-chlorethyl)-aminomethyl]-4-nitrophenol
2-Di-(2-chlor-aethyl)-aminomethyl-4-nitro-phenol
Bis(2-chloroethyl)aminomethyl-4-hydroxynitrobenzene
Chemical & Physical Properties
[ Density]:
1.382g/cm3
[ Boiling Point ]:
375.5ºC at 760 mmHg
[ Molecular Formula ]:
C11H14Cl2N2O3
[ Molecular Weight ]:
293.14600
[ Flash Point ]:
180.9ºC
[ Exact Mass ]:
292.03800
[ PSA ]:
69.29000
[ LogP ]:
3.10320
[ Index of Refraction ]:
1.589
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SJ7781100
- CHEMICAL NAME :
- Phenol, 2-((bis(2-chloroethyl)amino)methyl)-4-nitro-
- CAS REGISTRY NUMBER :
- 56537-91-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C11-H14-Cl2-N2-O3
- MOLECULAR WEIGHT :
- 293.17
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- RCBUAU Revista de Chimie (Bucharest). (Rompresfilatelia, POB 12-201, Bucharest, Romania) V.1- 1950- Volume(issue)/page/year: 30,1073,1979 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 35 mg/kg
- SEX/DURATION :
- female 1-7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- IJMRAQ Indian Journal of Medical Research. (Indian Council of Medical Research, Ansari Nagar, New Delhi 110 029, India) V.1- 1913- Volume(issue)/page/year: 64,244,1976