3-Nitrobenzenecarboximidamide
Names
[ CAS No. ]:
56406-50-9
[ Name ]:
3-Nitrobenzenecarboximidamide
[Synonym ]:
3-Nitrobenzenecarboximidamide
MFCD00012844
3-nitrobenzenecarboxamidine hydrochloride
3-nitrobenzamidinium chloride
3-nitrobenzenecarboximidamide hydrochloride
3-nitrobenzenecarboxamidine,chloride
m-nitrobenzamidine hydrochloride
Benzenecarboximidamide, 3-nitro-
EINECS 260-159-9
3-nitrobenzamidine hydrochloride
m-nitrobenzamidinium chloride
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
301.7±44.0 °C at 760 mmHg
[ Melting Point ]:
245-248ºC(lit.)
[ Molecular Formula ]:
C7H8ClN3O2
[ Molecular Weight ]:
165.149
[ Flash Point ]:
136.3±28.4 °C
[ Exact Mass ]:
165.053833
[ PSA ]:
95.69000
[ LogP ]:
0.72
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.642
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CV6295000
- CHEMICAL NAME :
- Benzamidine, m-nitro-, hydrochloride
- CAS REGISTRY NUMBER :
- 56406-50-9
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C7-H7-N3-O2.Cl-H
- MOLECULAR WEIGHT :
- 201.63
- WISWESSER LINE NOTATION :
- WNR CYZUM &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 84,16,1945
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
CV6295000
[ HS Code ]:
2925290090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925290090
[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Cancer Clin. Trials 3(1) , 55-62, (1980)
Normal tissue toxicity of nitroaromatic radiosensitizers may originate in radiosensitizer/nitroreductase interaction. A study of two mammalian cell nitroreductases, xanthine oxidase and NADH cytochrom...
Transformations of (Z)-2-benzoylamino-4-dimethylamino-2-oxo-3-butene and (E)-3-benzoylamino-4-cyano-2-oxo-3-butene into pyrimidine, pyrazole and isoxazole derivatives. Bratušek U, et al.ARKIVOC 77 , 86, (2003)