Myrtenal

Names

[ CAS No. ]:
564-94-3

[ Name ]:
Myrtenal

[Synonym ]:
(1R,5S)-6,6-dimethyl-bicyclo[3.3.1]hept-2-en-2-carbaldehyde
pin-2-ene-1-carbaldehyde
2-Norpinene-2-carboxaldehyde,6,6-dimethyl
EINECS 209-274-8
(1R)-(-)-MYRTENAL
6,6-dimethyl-2-norpinene-2-carboxaldehyd
Pin-2-en-1-carbaldehyd
MFCD00074768
Pina-2-ene-10-al
(-)-1R-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-carboxaldehyde
(R)-mirtenal
Benihinal
(R)-6,6-dimethylbicyclo[3.3.1]hept-2-en-2-carboxaldehyde
2-Formyl-6,6-dimethylbicyclo(3.1.1)hept-2-ene

Biological Activity

[Description]:

Myrtenal ((±)-Myrtenal) is a monoterpene that acts as an antineoplastic agent. Myrtenal inhibits liver cancer by preventing DEN-PB-induced upregulation of TNF-α protein expression.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Babu LH, et al. Myrtenal, a natural monoterpene, down-regulates TNF-α expression and suppresses carcinogen-induced hepatocellular carcinoma in rats. Mol Cell Biochem. 2012 Oct;369(1-2):183-93.

Chemical & Physical Properties

[ Density]:
1.061g/cm3

[ Boiling Point ]:
215.7ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₄O

[ Molecular Weight ]:
150.22

[ Flash Point ]:
78.9ºC

[ Exact Mass ]:
150.10400

[ PSA ]:
17.07000

[ LogP ]:
2.17770

[ Index of Refraction ]:
n20/D 1.504

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DT5180000

CHEMICAL NAME :: Bicyclo(3.1.1)hept-2-ene-2-carboxaldehyde, 6,6-dimethyl-

CAS REGISTRY NUMBER :: 564-94-3

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H14-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,329,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 170 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,329,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,329,1988

Safety Information

[ Safety Phrases ]:
S23-S24/25

[ WGK Germany ]:
2

[ RTECS ]:
DT5180000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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