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Pildralazine

Names

[ CAS No. ]:
56393-22-7

[ Name ]:
Pildralazine

Chemical & Physical Properties

[ Density]:
1.302g/cm3

[ Boiling Point ]:
486ºC at 760mmHg

[ Molecular Formula ]:
C8H17Cl2N5O

[ Molecular Weight ]:
270.15900

[ Flash Point ]:
247.7ºC

[ Exact Mass ]:
269.08100

[ PSA ]:
87.30000

[ LogP ]:
1.95650

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UR6040000
CHEMICAL NAME :
Pyridazine, 3-hydrazino-6-((2-hydroxypropyl)methylamino)-, dihydrochloride
CAS REGISTRY NUMBER :
56393-22-7
LAST UPDATED :
199112
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H15-N5-O.2Cl-H
MOLECULAR WEIGHT :
270.20
WISWESSER LINE NOTATION :
T6NNJ CMZ F1M1YQ1 &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1230 mg/kg
TOXIC EFFECTS :
Cardiac - pulse rate increase, without fall in BP Vascular - BP lowering not characterized in autonomic section
REFERENCE :
PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 8,295,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
355 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 8,295,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1170 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 8,295,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
357 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PLRCAT Pharmacological Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 8,295,1976

Related Compounds

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