Isobutyramide
Names
[ CAS No. ]:
563-83-7
[ Name ]:
Isobutyramide
[Synonym ]:
2-methylpropaneamide
EINECS 209-265-9
Propanamide, 2-methyl-
isopropylformamide
IBA
iso-Butyleneamine
isobutyrimidicacid
Isobutyramide
isobutyric amide
MFCD00008019
Isobuytramide
2-Methylpropanamide
anhydrous dimethyl-acetamide
Methyl propionic acid amide
VX 366
2-methylpropionamide
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
221.4±8.0 °C at 760 mmHg
[ Melting Point ]:
127-131 °C(lit.)
[ Molecular Formula ]:
C4H9NO
[ Molecular Weight ]:
87.120
[ Flash Point ]:
87.7±18.4 °C
[ Exact Mass ]:
87.068413
[ PSA ]:
43.09000
[ LogP ]:
-0.36
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.418
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX1475000
- CHEMICAL NAME :
- Propanamide, 2-methyl-
- CAS REGISTRY NUMBER :
- 563-83-7
- BEILSTEIN REFERENCE NO. :
- 1737615
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C4-H9-N-O
- MOLECULAR WEIGHT :
- 87.14
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5439939
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
22
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
TX1475000
[ HS Code ]:
2924199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924199090
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
PLoS ONE 11 , e0145212, (2016)
Poor outcome in response to hepatitis C virus, including higher viral load, hepatocellular carcinoma and cirrhosis, is more associated with men and postmenopausal women than with premenopausal women a...
Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin.Blood 101(5) , 2001-7, (2003)
Pharmacologic stimulation of fetal hemoglobin (HbF) expression may be a promising approach for the treatment of beta-thalassemia. In this study, we have investigated the HbF-inducing activity and mole...
Effects of ketoacidosis on rat apolipoprotein A1 gene expression: a link with acidosis but not with ketones.J. Mol. Endocrinol. 25(1) , 129-39, (2000)
To determine if ketoacidosis contributes to reduced apolipoprotein A1 (apoA1) expression in insulin-deficient diabetic rats, we examined the regulation of apoA1 gene expression in response to changes ...