Descarbamoyl Cefuroxime

Names

[ Name ]:
Descarbamoyl Cefuroxime

[Synonym ]:
7-PHENYLACETAMIDE-3-CHLOROMETHYL-CEPHALOSPORANIC ACID P-METHOXYBENZYL ESTER
Descarbamoyl Cefuroxime
GCLE:INTERMEDIATE FOR CEPHALOSPORIN
3-chloromethyl-7-phenylacetylaminocephalosporanic acid p-methoxybenzyl ester
7-PHENYLACETAMIDO-3-CHLOROMETHYLCEPHEM-4-CARBONICACID-PARA-METHOXYBENZYLESTER
7-phenylacetamido-3-chloromethylcephem-4-carbonicacidp-methoxybenzylester
7-PHENYLACETAMINO-3-CHLOROMETHYL-3-CEPHEM4-CARBOXYLIC ACID P-METHOXYBENZYL ESTER
Cefuroxime Impurity 4

Biological Activity

[Description]:

Descarbamoyl cefuroxime is a degradation product of Cefuroxime. Descarbamoyl cefuroxime is also an intermediate for the synthesis of Cephalosporin antibiotics[1][2].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Vercheval C, et al. Stability of 90 mg/mL cefuroxime sodium solution for administration by continuous infusion. J Chemother. 2018 Oct - Dec;30(6-8):371-374.

[2]. Takaya T, et al. Studies on beta-lactam antibiotics. III. Synthesis and enzymatic stability of 3-acyloxymethyl-7 beta-[(Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-cephem-4-carboxylic acids. J Antibiot (Tokyo). 1981 Oct;34(10):1300-10.

Chemical & Physical Properties

[ Density]:
1.72g/cm3

[ Molecular Formula ]:
C₁₅H₁₅N₃O₇S

[ Molecular Weight ]:
381.36100

[ Exact Mass ]:
381.06300

[ PSA ]:
170.46000

[ LogP ]:
0.13920

[ Index of Refraction ]:
1.733

Descarbamoyl Cefuroxime

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds