N10-Methyl Pteroic Acid
Names
[ CAS No. ]:
5623-18-7
[ Name ]:
N10-Methyl Pteroic Acid
[Synonym ]:
4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-methylamino]benzoic acid
4-[Methyl[(2-Amino-4-Hydroxypteridine)-6-Ylmethyl]Amino]Benzoic Acid
Methotrexate Impurity 4
Chemical & Physical Properties
[ Density]:
1.58g/cm3
[ Boiling Point ]:
668.3ºC at 760 mmHg
[ Molecular Formula ]:
C15H14N6O3
[ Molecular Weight ]:
326.31000
[ Flash Point ]:
357.9ºC
[ Exact Mass ]:
326.11300
[ PSA ]:
138.09000
[ LogP ]:
1.21110
[ Index of Refraction ]:
1.757
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DG2800000
- CHEMICAL NAME :
- Benzoic acid, p-((N-(2-amino-4-hydroxy)pteridin-6-ylmethyl)-N-methy lamino)-
- CAS REGISTRY NUMBER :
- 5623-18-7
- BEILSTEIN REFERENCE NO. :
- 0338741
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C15-H14-N6-O3
- MOLECULAR WEIGHT :
- 326.35
- WISWESSER LINE NOTATION :
- T66 BN DN GN JNJ CZ EQ H1N1&R BVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,686,1955