10b,10c-Ethano-1,4-methano-4H,9H-oxepino[3,4,5-ij]oxireno[b]quinolizin-2(1H)-one,hexahydro-12-methyl-, (1S,4R,4aS,9aR,10aS,10bS,10cS,12R)- (9CI)
Names
[ CAS No. ]:
559-49-9
[ Name ]:
10b,10c-Ethano-1,4-methano-4H,9H-oxepino[3,4,5-ij]oxireno[b]quinolizin-2(1H)-one,hexahydro-12-methyl-, (1S,4R,4aS,9aR,10aS,10bS,10cS,12R)- (9CI)
[Synonym ]:
Annotinin
ANNOTININE
Chemical & Physical Properties
[ Density]:
1.37g/cm3
[ Boiling Point ]:
462ºC at 760mmHg
[ Molecular Formula ]:
C16H21NO3
[ Molecular Weight ]:
275.34300
[ Flash Point ]:
233.2ºC
[ Exact Mass ]:
275.15200
[ PSA ]:
42.07000
[ LogP ]:
1.12760
[ Index of Refraction ]:
1.631
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CA1190000
- CHEMICAL NAME :
- Annotinine
- CAS REGISTRY NUMBER :
- 559-49-9
- BEILSTEIN REFERENCE NO. :
- 0030714
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C16-H21-N-O3
- MOLECULAR WEIGHT :
- 275.38
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 115 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 34,197,1945