Fmoc-NH-PEG4-CH2CH2COOH

Names

[ Name ]:
Fmoc-NH-PEG4-CH2CH2COOH

[Synonym ]:
Fmoc-15-Amino-4,7,10,13-Tetraoxapentadecanoic Acid
5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester
Fmoc-PEG4-propionic acid

Biological Activity

[Description]:

Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14.

Chemical & Physical Properties

[ Density]:
1.219

[ Molecular Formula ]:
C₂₆H₃₃NO₈

[ Molecular Weight ]:
487.54200

[ Exact Mass ]:
487.22100

[ PSA ]:
112.55000

[ LogP ]:
3.45710

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
24/25