N,N-dinitrosohomopiperazine
Names
[ CAS No. ]:
55557-00-1
[ Name ]:
N,N-dinitrosohomopiperazine
[Synonym ]:
Dinitrosohomopiperazine
LS-7359
1H-1,4-DIAZEPINE,HEXAHYDRO-1,4-DINITROSO
N,N-Dinitrosohomopiperazine
N,N'-Dinitroso-homopiperazin
Chemical & Physical Properties
[ Density]:
1.43g/cm3
[ Boiling Point ]:
403.1ºC at 760 mmHg
[ Molecular Formula ]:
C5H10N4O2
[ Molecular Weight ]:
158.15800
[ Flash Point ]:
197.6ºC
[ Exact Mass ]:
158.08000
[ PSA ]:
65.34000
[ LogP ]:
0.23270
[ Index of Refraction ]:
1.622
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HM3950000
- CHEMICAL NAME :
- 1H-1,4-Diazepine, hexahydro-1,4-dinitroso-
- CAS REGISTRY NUMBER :
- 55557-00-1
- BEILSTEIN REFERENCE NO. :
- 0147155
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C5-H10-N4-O2
- MOLECULAR WEIGHT :
- 158.19
- WISWESSER LINE NOTATION :
- T7N DNTJ ANO DNO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 65 mg/kg/2Y-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 105 mg/kg/30W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1530 mg/kg/31W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Gastrointestinal - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 5 umol/L
- REFERENCE :
- TCMUE9 Topics in Chemical Mutagenesis. (Plenum Pub. Corp., 233 Spring Street, New York, NY 10013) V.1- 1984- Volume(issue)/page/year: 1,129,1984