Iprozilamine
Names
[ CAS No. ]:
55477-19-5
[ Name ]:
Iprozilamine
[Synonym ]:
Iprozilamine [INN]
[4-chloro-6-(4-methyl-piperazin-1-yl)-5-methylsulfanyl-pyrimidin-2-yl]-isopropyl-amine
Iprozilamina [INN-Spanish]
Iprozilaminum
4-Chloro-2-isopropylamino-6-(4-methylpiperazino)-5-methylthiopyrimidine
2-Isopropylamino-4-(4-methylpiperazino)-5-methylmercapto-6-chlorpyrimidin
Pyrimidine,4-chloro-2-isopropylamino-6-(4-methylpiperazino)-5-methylthio
Iprozilaminum [INN-Latin]
Iprozilamina
Iprozilamine
2-Isopropylamino-4-methylpiperazino-6-chloro-5-methylthio-pyrimidine
Chemical & Physical Properties
[ Density]:
1.26g/cm3
[ Boiling Point ]:
449.7ºC at 760 mmHg
[ Molecular Formula ]:
C13H22ClN5S
[ Molecular Weight ]:
315.86500
[ Flash Point ]:
225.8ºC
[ Exact Mass ]:
315.12800
[ PSA ]:
69.59000
[ LogP ]:
2.49990
[ Index of Refraction ]:
1.605
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UV8111000
- CHEMICAL NAME :
- Pyrimidine, 4-chloro-2-isopropylamino-6-(4-methylpiperazino)-5-me thylthio-
- CAS REGISTRY NUMBER :
- 55477-19-5
- BEILSTEIN REFERENCE NO. :
- 0674548
- LAST UPDATED :
- 199703
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C13-H22-Cl-N5-S
- MOLECULAR WEIGHT :
- 315.91
- WISWESSER LINE NOTATION :
- T6N DNTJ A1 D- DT6N CNJ BMY1&1 ES1 FG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 455 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,553,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,553,1975