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Penicillide

Names

[ CAS No. ]:
55303-92-9

[ Name ]:
Penicillide

[Synonym ]:
1,2,4-triazin-5-ol,6-(2-aminophenyl)-3-(methylthio)
6-(2-amino-phenyl)-3-methylsulfanyl-4h-[1,2,4]triazin-5-one

Biological Activity

[Description]:

Penicillide (Vermixocin A), isolated from Talaromyces derxii cultivated on rice, shows inhibitory activity against acyl-CoA:cholesterol acyltransferase (ACAT)[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. H Nishida,et al. Purpactins, new inhibitors of acyl-CoA:cholesterol acyltransferase produced by Penicillium purpurogenum. III. Chemical modification of purpactin A. J Antibiot (Tokyo). 1991 Feb;44(2):152-9.

Chemical & Physical Properties

[ Density]:
1.242g/cm3

[ Boiling Point ]:
606.1ºC at 760 mmHg

[ Molecular Formula ]:
C10H10N4OS

[ Molecular Weight ]:
234.27800

[ Flash Point ]:
214.3ºC

[ Exact Mass ]:
234.05800

[ PSA ]:
110.22000

[ LogP ]:
2.12950

[ Index of Refraction ]:
1.582

[ Storage condition ]:
-20°C