1-Adamantanecarboxamide

Names

[ Name ]:
1-Adamantanecarboxamide

[Synonym ]:
Adamantane-1-carboxamide
MFCD00077200
1-Adamantanecarboxamide
EINECS 234-074-2
Tricyclo[3.3.1.1]decane-1-carboxamide

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
343.3±9.0 °C at 760 mmHg

[ Melting Point ]:
188-190 °C(lit.)

[ Molecular Formula ]:
C₁₁H₁₇NO

[ Molecular Weight ]:
179.259

[ Flash Point ]:
161.4±18.7 °C

[ Exact Mass ]:
179.131012

[ PSA ]:
43.09000

[ LogP ]:
1.65

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.572

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU4452000

CHEMICAL NAME :: 1-Adamantanecarboxamide

CAS REGISTRY NUMBER :: 5511-18-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H17-N-O

MOLECULAR WEIGHT :: 179.29

WISWESSER LINE NOTATION :: L66 B6/B-H/DI A B- C 1B ITJ BVZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 10,579,1976

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AU4452000

[ HS Code ]:
2924299090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

[Comparative study of the mechanism of inhibition of Sindbis virus reproduction by adamantane derivatives: remantadine and amide of 1-adamantane carboxylic acid].

Antibiot. Khimioter. 41(7-8) , 26-30, (1996)

Amide of 1-adamantane carboxylic acid (AACA), the same as remantadine, was shown to have no antiviral action and any influence on the efficiency of the Sindbis virus adsorption. However, it significan...

Capture of a single molecule in a nanocavity.

Science 291(5504) , 636-40, (2001)

We describe a heptameric protein pore that has been engineered to accommodate two different cyclodextrin adapters simultaneously within the lumen of a transmembrane beta barrel. The volume between the...