DL-071-IT

Names

[ Name ]:
DL-071-IT

[Synonym ]:
1(3H)-Isobenzofuranone,7-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-,hydrochloride
DL 071 IT
DL-071-IT

Biological Activity

[Description]:

DL 071IT is a potent non-selective beta-adrenergic receptor blocker. DL 071IT exhibits intrinsic sympathomimetic activity and weak membrane stabilizing activity. DL 071IT reduces exercise heart rate and systolic blood pressure, and even significantly lowers resting heart rate[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Research Areas >> Endocrinology

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

[Target]

β adrenergic receptor

[References]

[1]. Radice M, et al. Pharmacodynamic studies in man of the beta-adrenoceptor antagonist DL 071 IT. Eur J Clin Pharmacol. 1979 Sep;16(2):87-90.

Chemical & Physical Properties

[ Boiling Point ]:
485.4ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₂ClNO₄

[ Molecular Weight ]:
315.79

[ Flash Point ]:
247.3ºC

[ Exact Mass ]:
315.12400

[ PSA ]:
67.79000

[ LogP ]:
2.67770

[ Storage condition ]:
-20℃

Related Compounds

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