Amisometradine
Names
[ CAS No. ]:
550-28-7
[ Name ]:
Amisometradine
[Synonym ]:
Aminoisometradin
6-Amino-1-metallyl-3-methylpyrimidine-2,4-dione
AMISOMETRADINE
Aminoisometradine
Amisometradin
Rolicton
6-Amino-1-methallyl-3-methyl-1H-pyrimidin-2,4-dion
Amisometradinum [INN-Latin]
6-Amino-3-methyl-1-(2-methylallyl)uracil
Uracil,6-amino-3-methyl-1-(2-methylallyl)
6-amino-1-methallyl-3-methyl-1H-pyrimidine-2,4-dione
6-amino-3-methyl-1-(2-methyl-allyl)-1H-pyrimidine-2,4-dione
Amisometradina [INN-Spanish]
Chemical & Physical Properties
[ Density]:
1.176g/cm3
[ Boiling Point ]:
292.1ºC at 760 mmHg
[ Molecular Formula ]:
C9H13N3O2
[ Molecular Weight ]:
195.21800
[ Flash Point ]:
130.5ºC
[ Exact Mass ]:
195.10100
[ PSA ]:
70.02000
[ LogP ]:
0.28650
[ Index of Refraction ]:
1.537
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YQ8800000
- CHEMICAL NAME :
- Uracil, 6-amino-3-methyl-1-(2-methylallyl)-
- CAS REGISTRY NUMBER :
- 550-28-7
- BEILSTEIN REFERENCE NO. :
- 0182347
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C9-H13-N3-O2
- MOLECULAR WEIGHT :
- 195.25
- WISWESSER LINE NOTATION :
- T6NVNVJ A1Y1&U1 C1 FZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1560 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 126,400,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 515 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 126,400,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 610 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,79,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 415 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,79,1989
Safety Information
[ HS Code ]:
2933599090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%