(-)-Isoproterenol tartrate

Names

[ Name ]:
(-)-Isoproterenol tartrate

[Synonym ]:
(-Isoproterenol hydrogen tartrate salt
(-)-isoprenalinetartrate
isolevine
isoprenaline tartrate dihydrate
l-isoprenalinebitartrate
(-)-isoprenaline (+)-bitartrate salt
isopropylnoradrenalinebitartrate
isolevin

Chemical & Physical Properties

[ Boiling Point ]:
417.5ºCat 760 mmHg

[ Melting Point ]:
80-83ºC

[ Molecular Formula ]:
C₁₅H₂₃NO₉

[ Molecular Weight ]:
361.34400

[ Flash Point ]:
179.7ºC

[ Exact Mass ]:
361.13700

[ PSA ]:
187.78000

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ8960000

CAS REGISTRY NUMBER :: 54750-10-6

LAST UPDATED :: 198912

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C11-H17-N-O3.C4-H6-O6

MOLECULAR WEIGHT :: 361.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3768 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 21,1,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 849 mg/kg

TOXIC EFFECTS :: Vascular - regional or general arteriolar or venous dilation

REFERENCE :: SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 21,1,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 21,1,1953

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Articles

Beta-adrenergic receptor activation facilitates induction of a protein synthesis-dependent late phase of long-term potentiation.

J. Neurosci. 25(13) , 3294-303, (2005)

Long-term potentiation (LTP) is activity-dependent enhancement of synaptic strength that can critically regulate long-term memory storage. Like memory, LTP exhibits at least two mechanistically distin...

Effects of noradrenaline on frequency tuning of rat auditory cortex neurons.

Eur. J. Neurosci. 9(4) , 833-47, (1997)

The selectivity of rat auditory cortex neurons for pure tone frequency was studied during and after ionophoretic application (5-40 nA) of noradrenaline in urethane-anaesthetized rats. The dominant eff...

[Effect of synaptically active substances on the hyperthermic effect of prostaglandin E2 in rats].

Biull. Eksp. Biol. Med. 91(3) , 304-5, (1981)

It was established in experiments on unanesthetized rats given intraventricular injections of drugs that hyperthermic effect of prostaglandin E2 (PGE2) was markedly weakened by administering clofelin ...