Guanidinoethyl sulfonate

Names

[ CAS No. ]:
543-18-0

[ Name ]:
Guanidinoethyl sulfonate

[Synonym ]:
Guanidinoethyl Sulfonate
2-(diaminomethylideneamino)ethanesulfonic acid

Biological Activity

[Description]:

Guanidinoethyl sulfonate (Taurocyamine), a transport antagonist of taurine, induces much urinary taurine excretion with a resulting decrease in the tissue taurine content and readily produces taurine-deficient fetal rats in pregnant rats[1]. Guanidinoethyl sulfonate, a structural analogue of taurine, acts as a competitive inhibitor of taurine transport[2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[References]

[1]. K Ejiri, et al. Effect of guanidinoethyl sulfonate on taurine concentrations and fetal growth in pregnant rats. Biol Neonate. 1987;51(4):234-40.

[2]. Luz M Suárez, et al. The taurine transporter substrate guanidinoethyl sulfonate mimics the action of taurine on long-term synaptic potentiation. Amino Acids. 2016 Nov;48(11):2647-2656.

Chemical & Physical Properties

[ Density]:
1.73g/cm3

[ Melting Point ]:
263-265ºC

[ Molecular Formula ]:
C₃H₉N₃O₃S

[ Molecular Weight ]:
167.18700

[ Exact Mass ]:
167.03600

[ PSA ]:
124.65000

[ LogP ]:
0.62900

[ Index of Refraction ]:
1.618

MSDS

Click to get detail MSDS

Safety Information

[ Risk Phrases ]:
34

[ Safety Phrases ]:
S26-S36-S37-S39

[ RIDADR ]:
UN 3261

[ HS Code ]:
2925290090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%