6-amino-2-methylheptan-2-ol,hydrochloride
Names
[ CAS No. ]:
543-15-7
[ Name ]:
6-amino-2-methylheptan-2-ol,hydrochloride
[Synonym ]:
6-hydroxy-6-methyl-2-heptylamine hydrochloride
Heptylon tropfen
6-amino-2-methyl-2-heptanol hydrochloride
Heptamyl tropfen
Coreptil
MFCD00013015
6-Amino-2-methyl-heptan-2-ol,Hydrochlorid
Delmiton
Arcor tropfen
Cardiosintol
Heptaminol HCl
Cortensor
EINECS 208-837-5
6-amino-2-methyl-heptan-2-ol,hydrochloride
heptaminol hydrochloride
Biological Activity
[Description]:
[Related Catalog]:
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
0.895g/cm3
[ Boiling Point ]:
250.1ºC at 760mmHg
[ Melting Point ]:
165-167 °C(lit.)
[ Molecular Formula ]:
C8H20ClNO
[ Molecular Weight ]:
181.70300
[ Flash Point ]:
105.1ºC
[ Exact Mass ]:
181.12300
[ PSA ]:
46.25000
[ LogP ]:
2.77710
[ Storage condition ]:
2-8℃
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MJ3240000
- CHEMICAL NAME :
- 2-Heptanol, 6-amino-2-methyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 543-15-7
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C8-H19-N-O.Cl-H
- MOLECULAR WEIGHT :
- 181.74
- WISWESSER LINE NOTATION :
- ZY1&3XQ1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 28 ug/kg
- TOXIC EFFECTS :
- Cardiac - pulse rate increase, without fall in BP Kidney, Ureter, Bladder - urine volume increased Skin and Appendages - sweating
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 103,178,1951
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 103,178,1951
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 670 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,515,1970
Safety Information
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
MJ3240000
[ HS Code ]:
2922199090
Customs
[ HS Code ]: 2922199090
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 827(2) , 199-204, (2005)
A study of the metabolism of isometheptene, an antispasmodic drug, in man and comparison with heptaminol metabolism, is presented in this paper. Isometheptene and two metabolites were detected in huma...
Double-blind plethysmographic study of venous effects of heptaminol adenosine phosphate in patients with primary varicose veins.Eur. J. Clin. Pharmacol. 37(1) , 37-40, (1989)
Changes in venous haemodynamics were studied after administration of a single dose of 3 g Heptaminol Adenosine Phosphate (HAP) to 30 subjects with primary varicose veins. Strain gauge plethysmography ...
Measurement of lymphatic flow variation by noninvasive method cases of lymphedema.Angiology 43(7) , 567-71, (1992)
The purpose of this study was to measure the variations of lymphatic flow. A noninvasive isotopic method was used to achieve a functional exploration of lymphatic circulation. Fifteen subjects were us...