Agatolimod sodium

Names

[ CAS No. ]:
541547-35-7

[ Name ]:
Agatolimod sodium

Biological Activity

[Description]:

Agatolimod sodium (ODN 7909) is a class B CpG ODN and is a TLR9 agonist. Agatolimod sodium can be used as vaccine adjuvant. Agatolimod sodium can be used for the research of cancer. Sequence: 5’-TCGTCGTTTTGTCGTTTTGTCGTT-3’[1][2].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)
Research Areas >> Cancer

[Target]

TLR9


[In Vitro]

Agatolimod sodium (ODN 7909) (10 μg/mL; 24 and 48 h) increases radiation sensitivity of radiation-resistant human lung adenocarcinoma cell line by overexpression of TLR9[1].

[References]

[1]. Yan L, et al. CpG-ODN 7909 increases radiation sensitivity of radiation-resistant human lung adenocarcinoma cell line by overexpression of Toll-like receptor 9. Cancer Biother Radiopharm. 2013 Sep;28(7):559-64.  

[2]. Cooper CL, et al. Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine. Vaccine. 2004 Aug 13;22(23-24):3136-43.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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