2-Propenoic acid,3-(3,4-dimethoxyphenyl)-, methyl ester

Names

[ Name ]:
2-Propenoic acid,3-(3,4-dimethoxyphenyl)-, methyl ester

[Synonym ]:
Methyl 3,4-dimethoxycinnamate
3-(3,4-dimethoxyphenyl)-acrylic acid methyl ester
methyl (2E)-3-(3,4-dimethoxyphenyl)prop-2-enoate
methyl (E)-3-(3,4-dimethoxyphenyl)prop-2-enoate
methyl 3-(3,4-dimethoxyphenyl)-2-propenoate
2-Propenoic acid,3-(3,4-dimethoxyphenyl)-,methyl ester
3,4-O-Dimethylcaffeic acid methyl ester
methyl (E)-3,4-dimethoxycinnamate
Cinnamic acid,3,4-dimethoxy-,methyl ester
2-Propenoic acid,3-(3,4-dimethoxyphenyl)-,methyl ester,trans
3-(3',4'-dimethoxyphenyl)-(E)-propenoic acid methyl ester
Methyl 3-(3`,4`-Dimethoxyphenyl)propenoate
ferulic methyl ester

Biological Activity

[Description]:

Methyl 3,4-dimethoxycinnamate is an inhibitor of uredospore germination. Methyl 3,4-dimethoxycinnamate also inhibits global DNA methylation in in Hep3B cells[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Macko V, et al. Self-inhibitor of bean rust uredospores: methyl 3,4-dimethoxycinnamate. Science. 1970 Oct 30;170(3957):539-40.

[2]. Castro-Vazquez D, et al. Methyl benzoate and cinnamate analogs as modulators of DNA methylation in hepatocellular carcinoma. Chem Biol Drug Des. 2022 Aug;100(2):245-255.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₁₄O₄

[ Molecular Weight ]:
222.24

[ Exact Mass ]:
222.08900

[ PSA ]:
44.76000

[ LogP ]:
1.89000

[ Storage condition ]:
2-8℃

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

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