3,5-Diaminobenzoic acid

Names

[ CAS No. ]:
535-87-5

[ Name ]:
3,5-Diaminobenzoic acid

[Synonym ]:
5-carboxy-m-phenylenediamine
3,5-Diaminobenzoic acid
Benzoic acid, 3,5-diamino-
Benzoic acid,3,5-diamino
1-Carboxy-3,5-Diaminobenzene
3,5-Diamino Benzoic Acid
EINECS 208-621-0
3,5-Diaminobenzoesaeure
1,3-diaminobenzene-5-carboxylic acid
3,5-diaminobenzoicacid
MFCD00007807

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
459.1±35.0 °C at 760 mmHg

[ Melting Point ]:
235-238 °C (dec.)(lit.)

[ Molecular Formula ]:
C₇H₈N₂O₂

[ Molecular Weight ]:
152.151

[ Flash Point ]:
231.5±25.9 °C

[ Exact Mass ]:
152.058578

[ PSA ]:
89.34000

[ LogP ]:
-0.29

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.711

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG6186000

CHEMICAL NAME :: Benzoic acid, 3,5-diamino-

CAS REGISTRY NUMBER :: 535-87-5

BEILSTEIN REFERENCE NO. :: 2086484

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H8-N2-O2

MOLECULAR WEIGHT :: 152.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 10 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,183,1988

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DG6186000

[ HS Code ]:
29224995

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

A specific fluorometric assay for hexosamines in glycosaminoglycans, based on deaminative cleavage with nitrous acid.

Anal. Biochem. 223(2) , 266-73, (1994)

Glycosaminoglycan (GAG) hexosamines were measured after deacetylation (2 h acid hydrolysis), deaminative cleavage by nitrous acid, and coupling of the 2,5-anhydro sugars thus produced with 3,5-diamino...

[Improved fluorometric method for DNA microanalysis].

Izv. Akad. Nauk SSSR Biol. (2) , 217-22, (1984)

Interference of Bis-Tris buffer with the diaminobenzoic acid fluorescence assay used to quantify DNA.

Mutat. Res. 226(4) , 263-6, (1989)