1-(Piperidinomethyl)-2-naphthol
Names
[ CAS No. ]:
5342-95-0
[ Name ]:
1-(Piperidinomethyl)-2-naphthol
[Synonym ]:
piperidinomethyl-2-naphthol
1-piperidinomethylene-2-naphthol
1-Piperidinomethyl-[2]naphthol
Ro 3-0514
1-piperidin-1-ylmethyl-naphthalen-2-ol
1-PIPERIDINOMETHYL-2-NAPHTHOL
1-(piperidin-1-ylmethyl)-2-naphthol
Chemical & Physical Properties
[ Density]:
1.158g/cm3
[ Boiling Point ]:
393.2ºC at 760mmHg
[ Melting Point ]:
93ºC
[ Molecular Formula ]:
C16H19NO
[ Molecular Weight ]:
241.32800
[ Flash Point ]:
198.8ºC
[ Exact Mass ]:
241.14700
[ PSA ]:
23.47000
[ LogP ]:
3.46920
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QL4905000
- CHEMICAL NAME :
- 2-Naphthol, 1-(piperidinomethyl)-
- CAS REGISTRY NUMBER :
- 5342-95-0
- BEILSTEIN REFERENCE NO. :
- 0185859
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C16-H19-N-O
- MOLECULAR WEIGHT :
- 241.36
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 12,194,1957
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 73,27,1941
Safety Information
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%