Ethyl (2-amino-1,3-thiazol-4-yl)acetate

Names

[ Name ]:
Ethyl (2-amino-1,3-thiazol-4-yl)acetate

[Synonym ]:
Ethyl 2-(2-aminothiazol-4-yl)acetate
MFCD00005330
Ethyl (2-amino-1,3-thiazol-4-yl)acetate
(2-Amino-4-thiazolyl)acetic Acid Ethyl Ester
Ethyl-2-(2-amino-4-thiazole-4-yl) acetate
EINECS 258-452-1
4-Thiazoleacetic acid, 2-amino-, ethyl ester
Ethyl (2-AMino-4-thiazolyl)acetate
Ethyl 2-Amino-4-Thiazoleacetate
ethyl 2-(2-amino-1,3-thiazol-4-yl)acetate
Ethyl 2-aminothiazole-4-acetate

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
318.5±17.0 °C at 760 mmHg

[ Melting Point ]:
92-94 °C(lit.)

[ Molecular Formula ]:
C₇H₁₀N₂O₂S

[ Molecular Weight ]:
186.232

[ Flash Point ]:
146.4±20.9 °C

[ Exact Mass ]:
186.046295

[ PSA ]:
93.45000

[ LogP ]:
0.66

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.576

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Dichloridobis[ethyl 2-(2-amino-1,3-thia-zol-4-yl)acetate-κ(2)O,N(3)]cadmium.

Acta Crystallogr. Sect. E Struct. Rep. Online 68(6) , m788-m789, (2012)

The asymmetric unit of the title compound, [CdCl(2)(C(7)H(10)N(2)O(2)S)(2)], contains two complex molecules with similar configurations. The Cd(II) atoms are each six-coordinated by two thiazole N and...

Bis(2-amino-thia-zole-4-acetato)aquazinc(II).

Acta Crystallogr. Sect. E Struct. Rep. Online 65(12) , m1517-m1517, (2009)

In the title compound, [Zn(C(5)H(5)N(2)O(2)S)(2)(H(2)O)], the central Zn atom (2 site symmetry) is five-coordinated by two N and three O atoms [Zn-N = 2.047 (3) Å, Zn-O = 2.099 (2) and 1.974 (4) Å] in...

Discovery of 3-(4-methanesulfonylphenoxy)-N-[1-(2-methoxy-ethoxymethyl)-1H-pyrazol-3-yl]-5-(3-methylpyridin-2-yl)-benzamide as a novel glucokinase activator (GKA) for the treatment of type 2 diabetes mellitus

Bioorg. Med. Chem. 22(7) , 2280-93, (2014)

Novel heteroaryl-containing benzamide derivatives were synthesized and screened using an in vitro assay measuring increases in glucose uptake and glucokinase activity stimulated by 10mM glucose in rat...