Fluprednisolone

Names

[ CAS No. ]:
53-34-9

[ Name ]:
Fluprednisolone

[Synonym ]:
F. I. 6150
fluprednisolone
EINECS 200-170-8
MFCD00200355
Isopredon
Prednisolone,6alpha-fluoro
6alpha-Fluoroprednisolone
Etadrol
Vladicort
Alphadrol

Biological Activity

[Description]:

6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research[1][2][3].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Schmidt KS, et al. In-house validation and factorial effect analysis of a liquid chromatography-tandem mass spectrometry method for the determination of corticosteroids in bovine and porcine muscle tissue. Anal Bioanal Chem. 2013 Jul;405(19):6287-97.

[2]. Laron Z, et al. The comparative effect of 6 alpha-fluoroprednisolone, 6 alpha-methylprednisolone, and hydrocortisone on linear growth of children with congenital adrenal virilism and Addison's disease. J Pediatr. 1968 Nov;73(5):774-82.

[3]. COLLINS EJ, et al. Influence of adrenal steroids on radio-calcium metabolism in young beagle dogs. Acta Endocrinol (Copenh). 1963 Mar;42:348-54.

Chemical & Physical Properties

[ Density]:
1.35 g/cm3

[ Boiling Point ]:
572.3ºC at 760 mmHg

[ Melting Point ]:
208 - 213ºC

[ Molecular Formula ]:
C₂₁H₂₇FO₅

[ Molecular Weight ]:
378.43400

[ Flash Point ]:
299.9ºC

[ Exact Mass ]:
378.18400

[ PSA ]:
94.83000

[ LogP ]:
1.50560

[ Index of Refraction ]:
1.597

MSDS

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Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds

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