Isomorellic acid

Names

[ Name ]:
Isomorellic acid

[Synonym ]:
(2E)-4-[(2S,17S)-12-Hydroxy-8,8,21,21-tetramethyl-5-(3-methyl-2-buten-1-yl)-14,18-dioxo-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4(13),5,9,11,15-pentaen-19-yl]-2-methyl-2-b 
utenoic acid
2-Butenoic acid, 2-methyl-4-[(5S,14aS)-3a,4,5,7-tetrahydro-8-hydroxy-3,3,11,11-tetramethyl-13-(3-methyl-2-buten-1-yl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-, (2E)-

Biological Activity

[Description]:

Isomorellic acid is a cytotoxic caged xanthone and can be used for cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

Isomorellic acid (44 h) 抑制 K562/ADR 和 K562/S 细胞，IC50 分别为 1.86±0.13 μg/mL 和 0.91±0.07 μg/mL[1]。

[References]

[1]. Han QB, et al. Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi. Chem Pharm Bull (Tokyo). 2006 Feb;54(2):265-7.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
777.6±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₃H₃₆O₈

[ Molecular Weight ]:
560.634

[ Flash Point ]:
251.8±26.4 °C

[ Exact Mass ]:
560.241028

[ LogP ]:
8.08

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.644

Related Compounds

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