Armepavine

Names

[ CAS No. ]:
524-20-9

[ Name ]:
Armepavine

[Synonym ]:
Alkaloid D, from Evonymus europaea
(R)-(-)-Armepavine
Evoeuropine
NSC 110381
Armepavine

Biological Activity

[Description]:

Armepavine, an active compound from Nelumbo nucifera, exerts not only anti-inflammatory effects on human peripheral blood mononuclear cells, but also immunosuppressive effects on T lymphocytes and on lupus nephritic mice. Armepavine inhibits TNF-α-induced MAPK and NF-κB signaling cascades[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Target]

p65

[References]

[1]. Weng TC, et al. Inhibitory effects of armepavine against hepatic fibrosis in rats. J Biomed Sci. 2009 Sep 2;16:78.

Chemical & Physical Properties

[ Density]:
1.151g/cm3

[ Boiling Point ]:
460.5ºC at 760 mmHg

[ Melting Point ]:
149-150 °C

[ Molecular Formula ]:
C₁₉H₂₃NO₃

[ Molecular Weight ]:
313.39100

[ Flash Point ]:
232.3ºC

[ Exact Mass ]:
313.16800

[ PSA ]:
41.93000

[ LogP ]:
3.11900

[ Index of Refraction ]:
1.584

Safety Information

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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