Yohimban-16-carboxylicacid, 17-hydroxy-, (16a,17a)-

Names

[ CAS No. ]:
522-87-2

[ Name ]:
Yohimban-16-carboxylicacid, 17-hydroxy-, (16a,17a)-

[Synonym ]:
yohimbine acid
YOHIMBINIC ACID MONOHYDRATE
yohimbinic acid
YOHIMBIC ACID HYDRATE
YOHIMBIC ACID
Yohimbic
YOHIMBIC ACID MONOHYDRATE

Biological Activity

[Description]:

Yohimbic acid is an amphoteric demethylated derivative of Yohimbine. Yohimbic acid exhibits vasodilatory action, and has the potential for osteoarthritis (OA) research[1][2][3].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Wang S, et, al. Significantly dysregulated genes in osteoarthritic labrum cells identified through gene expression profiling. Mol Med Rep. 2019 Aug; 20(2): 1716-1724.

[2]. HAMET R. [Sympatholytic activity and toxicity of an amphoteric demethylated derivative of yohimbine: yohimbic acid]. C R Hebd Seances Acad Sci. 1951 Oct 29;233(18):1069-71.

[3]. HAMET R. [Demonstration of the direct vasodilatory action of yohimbic acid and Py-tetrahydroquinoline]. C R Hebd Seances Acad Sci. 1960 Jun 27;250:4473-5.

Chemical & Physical Properties

[ Density]:
1.39g/cm3

[ Boiling Point ]:
600ºC at 760mmHg

[ Melting Point ]:
267-268ºC (dec.)(lit.)

[ Molecular Formula ]:
C₂₀H₂₄N₂O₃

[ Molecular Weight ]:
340.41600

[ Flash Point ]:
316.6ºC

[ Exact Mass ]:
340.17900

[ PSA ]:
76.56000

[ LogP ]:
2.49660

[ Index of Refraction ]:
1.702

Safety Information

[ Risk Phrases ]:
23/24/25

[ Safety Phrases ]:
26-28-36/37/39-45

[ RIDADR ]:
UN 1544 6.1/PG 3

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

Related Compounds

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