Mal-PEG6-acid

Names

[ Name ]:
Mal-PEG6-acid

[Synonym ]:
3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid

Biological Activity

[Description]:

Mal-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
578.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₃₁NO₁₀

[ Molecular Weight ]:
433.450

[ Flash Point ]:
303.5±30.1 °C

[ Exact Mass ]:
433.194794

[ LogP ]:
-2.16

[ Vapour Pressure ]:
0.0±3.5 mmHg at 25°C

[ Index of Refraction ]:
1.501

Related Compounds

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