3,3'-Diethylthiadicarbocyanine iodide
Names
[ CAS No. ]:
514-73-8
[ Name ]:
3,3'-Diethylthiadicarbocyanine iodide
[Synonym ]:
3,3'-diethyl-2,2'-thiadicarbocyanine iodide
PARTEL
MFCD00074829
DELVEX
TELMID
ANELMID
3-ethyl-2-<5-(3-ethyl-2(3H)-benzothiazolidene)-1,3-pentadienyl>benzothiazolium iodide
3,3′-Diethylthiadicarbocyanine iodide
DTDC
EINECS 208-186-7
NETOCYD
DTDCL
DEJO
NK 136
3,3'-diethylthiadicarbocyanine
3,3'-DIETHYLTHIADICARBOCYANINE IODIDE
DTDCI
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Melting Point ]:
249ºC
[ Molecular Formula ]:
C23H23IN2S2
[ Molecular Weight ]:
518.47700
[ Exact Mass ]:
518.03500
[ PSA ]:
65.29000
[ LogP ]:
2.58000
[ Appearance of Characters ]:
Powder | Green
[ Index of Refraction ]:
1.491
[ Storage condition ]:
Poison room
[ Water Solubility ]:
Soluble in methanol
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DL7060000
- CHEMICAL NAME :
- Benzothiazolium, 3-ethyl-2-(5-(3-ethyl-2-benzothiazolinylidene)-1,3-pe ntadienyl)-, iodide
- CAS REGISTRY NUMBER :
- 514-73-8
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C23-H23-N2-S2.I
- MOLECULAR WEIGHT :
- 518.50
- WISWESSER LINE NOTATION :
- T56 BNYSJ B2 CU2U2U1- CT56 BK DSJ B2 &I
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,897,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02015
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300-H315-H319-H335
[ Precautionary Statements ]:
P261-P264-P301 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
T+
[ Risk Phrases ]:
R28;R36/37/38
[ Safety Phrases ]:
S26-S28-S36/37-S45
[ RIDADR ]:
UN 2811
[ WGK Germany ]:
3
[ RTECS ]:
DL7060000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
Synthetic Route
Articles
J. Med. Chem. 52 , 3539-47, (2009)
A structure-activity relationship for symmetrical cyanine inhibitors of human tau aggregation was elaborated using a filter trap assay. Antagonist activity depended on cyanine heterocycle, polymethine...
Three-dimensional fluorescence lifetime tomography.Med. Phys. 32(4) , 992-1000, (2005)
Near-infrared fluorescence tomography using molecularly targeted lifetime-sensitive, fluorescent contrast agents have applications for early-stage cancer diagnostics. Yet, although the measurement of ...
Genetic screening using the colour change of a PNA-DNA hybrid-binding cyanine dye.Nucleic Acids Res. 30(2) , E3, (2002)
As the relationship between human genes and various malfunctions and diseases becomes revealed at an ever-increasing pace, the need arises for the development of rapid genetic screening methods for di...