Periplogenin

Names

[ CAS No. ]:
514-39-6

[ Name ]:
Periplogenin

[Synonym ]:
Desoxostrophanthidin
Bio-0181
Periplogenin

Biological Activity

[Description]:

Periplogenin is a naturally occurring furanocoumarin found in Angelica dahurica roots，with potent anti-psoriatic effects. Periplogenin induces adipocyte differentiation[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Zhang WJ, et al. Periplogenin induces necroptotic cell death through oxidative stress in HaCaT cells and ameliorates skin lesions in the TPA- and IMQ-induced psoriasis-like mouse models. Biochem Pharmacol. 2016 Apr 1;105:66-79.

[2]. Han HS, et al. Phellopterin isolated from Angelica dahurica reduces blood glucose level in diabetic mice. Heliyon. 2018 Mar; 4(3): e00577.

Chemical & Physical Properties

[ Melting Point ]:
245-248℃

[ Molecular Formula ]:
C₂₃H₃₄O₅

[ Molecular Weight ]:
390.51300

[ Exact Mass ]:
390.24100

[ PSA ]:
86.99000

[ LogP ]:
2.71920

[ Storage condition ]:
-20℃

Related Compounds

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