2-AP nitrate salt

Names

[ CAS No. ]:
51-16-1

[ Name ]:
2-AP nitrate salt

[Synonym ]:
2-Aminopurine nitrate
Purine,2-amino-,mononitrate
2-AP nitrate salt
1H-Purin-2-amine,mononitrate (9CI)
7h-purin-2-amine nitrate(1:1)
2-Aminopurine nitrate salt

Chemical & Physical Properties

[ Boiling Point ]:
616.3ºC at 760 mmHg

[ Molecular Formula ]:
C5H6N6O3

[ Molecular Weight ]:
198.14000

[ Flash Point ]:
362.9ºC

[ Exact Mass ]:
198.05000

[ PSA ]:
146.53000

[ LogP ]:
0.69180

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UO7505700
CHEMICAL NAME :
Purine, 2-amino-, mononitrate
CAS REGISTRY NUMBER :
51-16-1
LAST UPDATED :
199410
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C5-H5-N5.H-N-O3
MOLECULAR WEIGHT :
198.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Mold - Neurospora crassa
DOSE/DURATION :
500 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 177,61,1987

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
UO7505700

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

IL-10-dependent S100A8 gene induction in monocytes/macrophages by double-stranded RNA.

J. Immunol. 182 , 2258-2268, (2009)

The S100 calcium-binding proteins S100A8 and S100A9 are elevated systemically in patients with viral infections. The S100A8-S100A9 complex facilitated viral replication in human CD4(+) T lymphocytes l...

Novel role for the double-stranded RNA-activated protein kinase PKR: modulation of macrophage infection by the protozoan parasite Leishmania.

FASEB J. 24 , 617-626, (2010)

The evolution of Leishmania infection depends on the balance between microbicidal and suppressor macrophage functions. Double-stranded RNA (dsRNA)-activated protein kinase R (PKR), a classic antiviral...

Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication.

Virology 413 , 103-110, (2011)

We performed experiments to determine the effect of PKR activation on respiratory syncytial virus (RSV) replication. We first determined that RSV infection activates PKR which induces the phosphorylat...


More Articles