Soyasapogenol A

Names

[ CAS No. ]:
508-01-0

[ Name ]:
Soyasapogenol A

[Synonym ]:
soya sapogenol a
soyasapogenol a(p)

Biological Activity

[Description]:

Soyasapogenol A, a triterpene compound, isolated from the roots of Abrus cantoniensis. Soyasapogenol A directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α, which consequently results in the prevention of liver damage in the Concanavalin A-induced hepatitis model[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Inflammation/Immunology

[References]

[1]. Chiang TC, et al. Isolation and structural elucidation of some sapogenols from Abrus cantoniensis. Planta Med. 1982 Sep;46(1):52-5.

[2]. Kuzuhara H, et al. Protective effects of soyasapogenol A on liver injury mediated by immune response in a concanavalin A-induced hepatitis model. Eur J Pharmacol. 2000 Mar 10;391(1-2):175-81.

Chemical & Physical Properties

[ Melting Point ]:
308-312 °C

[ Molecular Formula ]:
C₃₀H₅₀O₄

[ Molecular Weight ]:
474.71600

[ Exact Mass ]:
474.37100

[ PSA ]:
80.92000

[ LogP ]:
5.08290

Related Compounds

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