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Pennogenin

Names

[ CAS No. ]:
507-89-1

[ Name ]:
Pennogenin

[Synonym ]:
(3β,25R)-Spirost-5-en-3,17-diol
Spirost-5-en-3,17-diol, (3β,25R)-

Biological Activity

[Description]:

Pennogenin is a bioactive component which can be isolated from T. govanianum rhizomes. Pennogenin exhibits significant in vitro inhibitory effect on release of ROS[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[In Vitro]

Pennogenin exhibits significant in vitro inhibitory effect on release of ROS from whole blood, with an IC50 of 5.0 µg/mL[1].

[References]

[1]. Shafiq Ur Rahman, et al. Beneficial Effects of Trillium govanianum Rhizomes in Pain and Inflammation. Molecules. 2016 Aug; 21(8): 1095.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
565.0±50.0 °C at 760 mmHg

[ Melting Point ]:
247°C (lit.)

[ Molecular Formula ]:
C27H42O4

[ Molecular Weight ]:
430.620

[ Flash Point ]:
295.5±30.1 °C

[ Exact Mass ]:
430.308319

[ LogP ]:
5.03

[ Vapour Pressure ]:
0.0±3.5 mmHg at 25°C

[ Index of Refraction ]:
1.579

Related Compounds