5-Hydroxy Topotecan Dihydrochloride (Mixture of Diastereomers)

Names

[ Name ]:
5-Hydroxy Topotecan Dihydrochloride (Mixture of Diastereomers)

[Synonym ]:
10-Hydroxy-9-[(dimethylamino)methyl]-5-hydroxy-(20S,5RS)-camptothecin Dihydrochloride Salt
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9,12-trihydroxy-, (4S)-
(4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9,12-trihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
>168° C (dec.)

[ Melting Point ]:
>168° C (dec.)

[ Molecular Formula ]:
C₂₃H₂₃N₃O₆・₂HCl

[ Molecular Weight ]:
510.37

[ Flash Point ]:
467.4±34.3 °C

[ Exact Mass ]:
437.158691

[ LogP ]:
-0.09

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Index of Refraction ]:
1.754

[ Water Solubility ]:
Soluble in DMSO, methanol, and water.