Shishijimicin C

Names

[ Name ]:
Shishijimicin C

Biological Activity

[Description]:

Shishijimicin C is a novel antitumor agent found from the Ascidian Didemnum proliferum. Shishijimicin C shows anti-tumor activity with highly potent cytotoxicities[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

Shishijimicin C (compound 3) (1.7-6.3 pg/mL) shows high cytotoxicity for 3Y1, Hela and P388 cells[1]. Cell Cytotoxicity Assay[1] Cell Line: 3Y1, Hela and P388 cells Concentration: 1.7-6.3 pg/mL Incubation Time: Result: Showed IC50 values of 4.8, 6.3, and 1.7 pg/mL for 3Y1, Hela and P388 cells, respectively.

[References]

[1]. Naoya Oku, et al. Shishijimicins A-C, novel enediyne antitumor antibiotics from the ascidian Didemnum proliferum(1). J Am Chem Soc. 2003 Feb 26;125(8):2044-5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₅H₅₀N₄O₁₂S₄

[ Molecular Weight ]:
967.16

Related Compounds

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