Org 42599 free base

Names

[ Name ]:
Org 42599 free base

Biological Activity

[Description]:

Org 42599 is a cell-permeant, allosterically binding, small-molecule agonist of luteinizing hormone (LH) receptor that rescues the folding and cell surface expression mutant mutant human LH receptors A593P and S616Y (EC50=70.8 nM).

[References]

References 1. Newton CL, et al. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7172-6. View Related Products by Target Luteinizing Hormone Receptor (LHR)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₃₀N₆O₃S₂

[ Molecular Weight ]:
514.663

Related Compounds

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