Isoetharine Hydrochloride

Names

[ CAS No. ]:
50-96-4

[ Name ]:
Isoetharine Hydrochloride

[Synonym ]:
Isoetharine Hydrochloride

Biological Activity

[Description]:

Isoetharine (hydrochloride) (compound I) is selective, short-acting and orally activeβ-agonistwhich is widely used as a bronchodilator in the research of inhalation therapy[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[In Vivo]

Isoetharine (hydrochloride) (I) (oral; 0, 800, 1400, 2000 and 2500 mg/kg/day; 2 weeks) is high variable of plasma levels in dose-ranging studies at 1 h after oral medication[1]. Animal Model: Sprague-Dawley rats[1] Dosage: 0, 800, 1400, 2000 and 2500 mg/kg Administration: oral; 0, 800, 1400, 2000 and 2500 mg/kg/day; 2 weeks Result: Observed highly variable of plasma levels in dose-ranging studies at 1 h after oral medication.

[References]

[1]. G B Park, et al. Determination of isoetharine in plasma by reversed-phase chromatography with amperometric detection. J Pharm Sci. 1982 Aug;71(8):932-4.

Chemical & Physical Properties

[ Boiling Point ]:
429.3ºC at 760mmHg

[ Molecular Formula ]:
C₁₃H₂₂ClNO₃

[ Molecular Weight ]:
275.77200

[ Flash Point ]:
156.7ºC

[ Exact Mass ]:
275.12900

[ PSA ]:
72.72000

[ LogP ]:
3.10070

Safety Information

[ HS Code ]:
2922509090

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%