3-Methyl-4-hydroxybenzoic acid

Names

[ CAS No. ]:
499-76-3

[ Name ]:
3-Methyl-4-hydroxybenzoic acid

[Synonym ]:
4-Hydroxy-m-toluic Acid
Benzoic acid, 4-hydroxy-3-methyl-
MFCD00270105
EINECS 207-890-1
4-Hydroxy-3-methylbenzoic acid
3-Methyl-4-hydroxybenzoic acid

Biological Activity

[Description]:

4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a healthy population.

[Related Catalog]:

Natural Products >> Acids and Aldehydes

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[In Vitro]

4-Hydroxy-3-methylbenzoic acid was isolated as the product of oxidation of 2,4-xylenol by cells inhibited with alpha alpha'-bipyridyl[1].

[References]

[1]. Chapman PJ, et al. The bacterial metabolism of 2,4-xylenol. Biochem J. 1968 Dec;110(3):491-8.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
331.3±30.0 °C at 760 mmHg

[ Melting Point ]:
173-177 °C

[ Molecular Formula ]:
C₈H₈O₃

[ Molecular Weight ]:
152.147

[ Flash Point ]:
168.4±21.1 °C

[ Exact Mass ]:
152.047348

[ PSA ]:
57.53000

[ LogP ]:
1.88

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.600

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;Xi: Irritant;

[ Risk Phrases ]:
R22;R37/38;R41

[ Safety Phrases ]:
S26-S36/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ HS Code ]:
2918290000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Articles

Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.

Clin. Chem. 40(6) , 862-6, (1994)

Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days...

Formation and occurrence of new polar iodinated disinfection byproducts in drinking water.

Chemosphere 144 , 2312-20, (2015)

During drinking water disinfection, iodinated disinfection byproducts (I-DBPs) can be generated through reactions between iodide, disinfectants, and natural organic matter. Drinking water I-DBPs have ...

Identification, toxicity and control of iodinated disinfection byproducts in cooking with simulated chlor(am)inated tap water and iodized table salt.

Water Res. 88 , 60-8, (2015)

Chlorine/chloramine residuals are maintained in drinking water distribution systems to prevent microbial contamination and microorganism regrowth. During household cooking processes (e.g., soup making...

Related Compounds

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