djenkolic acid

Names

[ CAS No. ]:
498-59-9

[ Name ]:
djenkolic acid

[Synonym ]:
(2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]sulfanylmethylsulfanyl]propanoic acid
S,S'-Methylenedi-L-cysteine
MFCD00063079
Djenkolic Acid
EINECS 207-863-4

Biological Activity

[Description]:

Djenkolic acid is a sulfur-containing non-protein amino acid naturally found in the djenkol beans of the Southeast Asian plant Archidendron jiringa. Djenkolic Acid often causes renal injury, including hypersensitivity to or a direct toxic effect of a djenkol bean metabolite, resulting in acute kidney injury and/or urinary tract obstruction by djenkolic acid crystals, sludge, and/or possible ureteral spasms[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Nur C Bunawan, et al. Djenkolism: case report and literature review. Int Med Case Rep J. 2014 Apr 16;7:79-84.

Chemical & Physical Properties

[ Density]:
1.501g/cm3

[ Boiling Point ]:
515.4ºC at 760 mmHg

[ Molecular Formula ]:
C₇H₁₄N₂O₄S₂

[ Molecular Weight ]:
254.32700

[ Flash Point ]:
265.5ºC

[ Exact Mass ]:
254.03900

[ PSA ]:
177.24000

[ LogP ]:
0.63470

[ Vapour Pressure ]:
5.2E-12mmHg at 25°C

[ Index of Refraction ]:
-65 ° (C=1, 1mol/L HCl)

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Risk Phrases ]:
R10:Flammable.

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
1993

[ WGK Germany ]:
3

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%