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carbohydrazide

Names

[ CAS No. ]:
497-18-7

[ Name ]:
carbohydrazide

[Synonym ]:
1,3-diaminourea
Carbonohydrazide
EINECS 207-837-2
MFCD00007591
Carbonic dihydrazide
carbohydrazide
Hydrazinecarbohydrazonic acid

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
150-153 °C(lit.)

[ Molecular Formula ]:
CH6N4O

[ Molecular Weight ]:
90.085

[ Exact Mass ]:
90.054161

[ PSA ]:
93.17000

[ LogP ]:
-1.94

[ Index of Refraction ]:
1.537

[ Stability ]:
Stable, but may explode if heated. Incompatible with strong acids, strong oxidizing agents.

MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H317-H411

[ Supplemental HS ]:
Risk of explosion if heated under confinement.

[ Precautionary Statements ]:
P273-P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38;R5

[ Safety Phrases ]:
S61-S36/37/39-S36/37

[ RIDADR ]:
UN3077

[ WGK Germany ]:
3

[ RTECS ]:
FF2625000

[ Packaging Group ]:
III

[ Hazard Class ]:
9

Synthetic Route

Precursor & DownStream

Articles

Tumour eradication using synchronous thermal ablation and Hsp90 chemotherapy with protein engineered triblock biopolymer-geldanamycin conjugates.

Int. J. Hyperthermia 30(8) , 550-64, (2014)

Hepatocellular carcinoma (HCC) suffers high tumour recurrence rate after thermal ablation. Heat shock protein 90 (Hsp90) induced post-ablation is critical for tumour survival and progression. A combin...

Synthesis and biological evaluation of benzimidazole-5-carbohydrazide derivatives as antimalarial, cytotoxic and antitubercular agents.

Bioorg. Med. Chem. 19 , 2023-9, (2011)

A series of N'-substituted-2-(5-nitrofuran or 5-nitrothiophen-2-yl)-3H-benzo[d]imidazole-5-carbohydrazide derivatives were synthesized and investigated for their abilities to inhibit β-hematin formati...

Synthesis and cytotoxic activity of novel 3-(1H-indol-3-yl)-1H-pyrazole-5-carbohydrazide derivatives.

Eur. J. Med. Chem. 46 , 5868-77, (2011)

A series of novel 3-(1H-indole-3-yl)-1H-pyrazole-5-carbohydrazide derivatives 4Ia-n, 4IIa-b and 6 were prepared by hydrazinolysis of ethyl 3-(1H-indole-3-yl)-1H-pyrazole-5-carboxylate with hydrazine h...


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Related Compounds