carbohydrazide
Names
[ CAS No. ]:
497-18-7
[ Name ]:
carbohydrazide
[Synonym ]:
1,3-diaminourea
Carbonohydrazide
EINECS 207-837-2
MFCD00007591
Carbonic dihydrazide
carbohydrazide
Hydrazinecarbohydrazonic acid
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Melting Point ]:
150-153 °C(lit.)
[ Molecular Formula ]:
CH6N4O
[ Molecular Weight ]:
90.085
[ Exact Mass ]:
90.054161
[ PSA ]:
93.17000
[ LogP ]:
-1.94
[ Index of Refraction ]:
1.537
[ Stability ]:
Stable, but may explode if heated. Incompatible with strong acids, strong oxidizing agents.
MSDS
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H317-H411
[ Supplemental HS ]:
Risk of explosion if heated under confinement.
[ Precautionary Statements ]:
P273-P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R20/21/22;R36/37/38;R5
[ Safety Phrases ]:
S61-S36/37/39-S36/37
[ RIDADR ]:
UN3077
[ WGK Germany ]:
3
[ RTECS ]:
FF2625000
[ Packaging Group ]:
III
[ Hazard Class ]:
9
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Int. J. Hyperthermia 30(8) , 550-64, (2014)
Hepatocellular carcinoma (HCC) suffers high tumour recurrence rate after thermal ablation. Heat shock protein 90 (Hsp90) induced post-ablation is critical for tumour survival and progression. A combin...
Synthesis and biological evaluation of benzimidazole-5-carbohydrazide derivatives as antimalarial, cytotoxic and antitubercular agents.Bioorg. Med. Chem. 19 , 2023-9, (2011)
A series of N'-substituted-2-(5-nitrofuran or 5-nitrothiophen-2-yl)-3H-benzo[d]imidazole-5-carbohydrazide derivatives were synthesized and investigated for their abilities to inhibit β-hematin formati...
Synthesis and cytotoxic activity of novel 3-(1H-indol-3-yl)-1H-pyrazole-5-carbohydrazide derivatives.Eur. J. Med. Chem. 46 , 5868-77, (2011)
A series of novel 3-(1H-indole-3-yl)-1H-pyrazole-5-carbohydrazide derivatives 4Ia-n, 4IIa-b and 6 were prepared by hydrazinolysis of ethyl 3-(1H-indole-3-yl)-1H-pyrazole-5-carboxylate with hydrazine h...