1-Methyl-1,2,3,4-tetrahydroisoquinoline

Names

[ Name ]:
1-Methyl-1,2,3,4-tetrahydroisoquinoline

[Synonym ]:
Isoquinoline, 1,2,3,4-tetrahydro-1-methyl-
1-Methyl-1,2,3,4-tetrahydroisoquinoline
1,2,3,4-Tetrahydro-1-methylisoquinoline 1MeTIQ

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
239.3±9.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₃N

[ Molecular Weight ]:
147.217

[ Flash Point ]:
100.0±14.2 °C

[ Exact Mass ]:
147.104797

[ PSA ]:
12.03000

[ LogP ]:
1.90

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.522

[ Storage condition ]:
2~8 °C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Comparative behavioral and neurochemical studies of R- and S-1-methyl-1,2,3,4-tetrahydroisoquinoline stereoisomers in the rat.

Pharmacol. Rep. 64(4) , 857-69, (2012)

1-Methyl-1,2,3,4-tetrahydroisoquinoline (1-MeTIQ) is present in human and mammalian brain as a racemate (R,S) of two stereoisomers: R- and S-1MeTIQ. The racemate is a mixture of the endogenous, synthe...

Important role of 3-methoxytyramine in the inhibition of cocaine sensitization by 1-methyl-1,2,3,4-tetrahydroisoquinoline: an in vivo microdialysis study.

Pharmacol. Rep. 62(6) , 983-97, (2010)

1-Methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) is an endogenous compound with neuroprotective and antidopaminergic activities. Our previous research has shown that 1MeTIQ prevents morphine addiction...

Determination method of 1-methyl-1,2,3, 4-tetrahydroisoquinoline, an endogenous parkinsonism-preventing substance, by radioimmunoassay.

Life Sci. 70(24) , 2871-83, (2002)

To develop a sensitive and simple assay method for 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ), an endogenous parkinsonism-preventing substance, we designed two kinds of 1MeTIQ-bovine serum album...