3-Formyl-6-isopropylchromone

Names

[ Name ]:
3-Formyl-6-isopropylchromone

[Synonym ]:
6-Isopropylchromone-3-carboxaldehyde
6-Isopropyl-4-oxo-4H-1-benzopyran-3-carboxaldehyde
6-Isopropyl-4-oxo-4H-chromene-3-carbaldehyde
MFCD00192183
4-oxo-6-propan-2-ylchromene-3-carbaldehyde

Chemical & Physical Properties

[ Density]:
1.259g/cm3

[ Boiling Point ]:
339.8ºC at 760mmHg

[ Melting Point ]:
98-100 °C(lit.)

[ Molecular Formula ]:
C₁₃H₁₂O₃

[ Molecular Weight ]:
216.23300

[ Flash Point ]:
150.2ºC

[ Exact Mass ]:
216.07900

[ PSA ]:
47.28000

[ LogP ]:
2.72890

[ Index of Refraction ]:
1.622

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Multidrug resistance reversal by 3-formylchromones in human colon cancer and human mdr1 gene-transfected mouse lymphoma cells.

In Vivo 20(5) , 645-9, (2006)

Several new 3-formylchromone derivatives proved to be modifiers of multidrug resistance in mouse lymphoma cells and in human Colo320 colon cancer cells. There is apparently a structure-activity relati...

Biological activity of 3-formylchromones and related compounds.

In Vivo 21(5) , 829-34, (2007)

Several 3-formylchromone derivatives were examined for their tumor cell-cytotoxic, anti-Helicobacter pylori, urease inhibitory and anti-HIV activity. Comparing their relative cytotoxicity against four...

Enthalpies of combustion and formation of 3-formylchromones. Flores H, et al.

Thermochim. Acta 450(1) , 35-37, (2006)